Identification of two novel Chlorotoxin derivatives CA4 and CTX-23 with chemotherapeutic and anti-angiogenic potential

Brain tumors are fast proliferating and destructive within the brain microenvironment. Effective chemotherapeutic strategies are currently lacking which combat this deadly disease curatively. The glioma-specific chloride ion channel represents a specific target for therapy. Chlorotoxin (CTX), a pept...

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Detalles Bibliográficos
Autores principales: Xu, Tengfei, Fan, Zheng, Li, Wenxin, Dietel, Barbara, Wu, Yingliang, Beckmann, Matthias W., Wrosch, Jana K., Buchfelder, Michael, Eyupoglu, Ilker Y., Cao, Zhijian, Savaskan, Nicolai E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735682/
https://www.ncbi.nlm.nih.gov/pubmed/26831010
http://dx.doi.org/10.1038/srep19799

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735682/
https://www.ncbi.nlm.nih.gov/pubmed/26831010
http://dx.doi.org/10.1038/srep19799

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