Mus81 knockdown improves chemosensitivity of hepatocellular carcinoma cells by inducing S‐phase arrest and promoting apoptosis through CHK1 pathway

As a critical endonuclease in DNA repair, Mus81 is traditionally regarded as a tumor suppressor, but recently correlated with the sensitivity of mitomycin C and 5‐fluorouracil in colon cancer and breast cancer cells. However, its role in chemosensitivity of other human malignancies still remains unk...

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Detalles Bibliográficos
Autores principales: Wu, Fan, Chen, Wei‐Jia, Yan, Lun, Tan, Guo‐Qian, Li, Wei‐Tao, Zhu, Xuan‐Jin, Ge, Xiao‐Chuan, Liu, Jian‐Wei, Wang, Bai‐Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735774/
https://www.ncbi.nlm.nih.gov/pubmed/26714930
http://dx.doi.org/10.1002/cam4.588

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735774/
https://www.ncbi.nlm.nih.gov/pubmed/26714930
http://dx.doi.org/10.1002/cam4.588

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