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Determination of ETV6‐RUNX1 genomic breakpoint by next‐generation sequencing

The t(12;21)(p13;q22) ETV6‐RUNX1 gene fusion is one of the most common chromosomal translocation in childhood acute lymphoblastic leukemia (ALL). It is associated with favorable prognosis. The identification of the genomic sequence of the breakpoint flanking regions of the ETV6‐RUNX1 translocation s...

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Detalles Bibliográficos
Autores principales: Jin, Yanliang, Wang, Xingwei, Hu, Shaoyan, Tang, Jingyan, Li, Benshang, Chai, Yihuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735785/
https://www.ncbi.nlm.nih.gov/pubmed/26711002
http://dx.doi.org/10.1002/cam4.579