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Proteolytic and non-proteolytic regulation of collective cell invasion: tuning by ECM density and organization

Cancer cells manoeuvre through extracellular matrices (ECMs) using different invasion modes, including single cell and collective cell invasion. These modes rely on MMP-driven ECM proteolysis to make space for cells to move. How cancer-associated alterations in ECM influence the mode of invasion rem...

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Detalles Bibliográficos
Autores principales: Kumar, Sandeep, Kapoor, Aastha, Desai, Sejal, Inamdar, Mandar M., Sen, Shamik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735823/
https://www.ncbi.nlm.nih.gov/pubmed/26832069
http://dx.doi.org/10.1038/srep19905