Icaritin requires Phosphatidylinositol 3 kinase (PI3K)/Akt signaling to counteract skeletal muscle atrophy following mechanical unloading

Counteracting muscle atrophy induced by mechanical unloading/inactivity is of great clinical need and challenge. A therapeutic agent that could counteract muscle atrophy following mechanical unloading in safety is desired. This study showed that natural product Icaritin (ICT) could increase the phos...

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Detalles Bibliográficos
Autores principales: ZHANG, Zong-Kang, LI, Jie, LIU, Jin, GUO, Baosheng, LEUNG, Albert, ZHANG, Ge, ZHANG, Bao-Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735824/
https://www.ncbi.nlm.nih.gov/pubmed/26831566
http://dx.doi.org/10.1038/srep20300

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735824/
https://www.ncbi.nlm.nih.gov/pubmed/26831566
http://dx.doi.org/10.1038/srep20300

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