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Icaritin requires Phosphatidylinositol 3 kinase (PI3K)/Akt signaling to counteract skeletal muscle atrophy following mechanical unloading
Counteracting muscle atrophy induced by mechanical unloading/inactivity is of great clinical need and challenge. A therapeutic agent that could counteract muscle atrophy following mechanical unloading in safety is desired. This study showed that natural product Icaritin (ICT) could increase the phos...
Autores principales: | ZHANG, Zong-Kang, LI, Jie, LIU, Jin, GUO, Baosheng, LEUNG, Albert, ZHANG, Ge, ZHANG, Bao-Ting |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735824/ https://www.ncbi.nlm.nih.gov/pubmed/26831566 http://dx.doi.org/10.1038/srep20300 |
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