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Imaging tumour cell heterogeneity following cell transplantation into optically clear immune-deficient zebrafish

Cancers contain a wide diversity of cell types that are defined by differentiation states, genetic mutations and altered epigenetic programmes that impart functional diversity to individual cells. Elevated tumour cell heterogeneity is linked with progression, therapy resistance and relapse. Yet, ima...

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Detalles Bibliográficos
Autores principales: Tang, Qin, Moore, John C., Ignatius, Myron S., Tenente, Inês M., Hayes, Madeline N., Garcia, Elaine G., Torres Yordán, Nora, Bourque, Caitlin, He, Shuning, Blackburn, Jessica S., Look, A. Thomas, Houvras, Yariv, Langenau, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735845/
https://www.ncbi.nlm.nih.gov/pubmed/26790525
http://dx.doi.org/10.1038/ncomms10358