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Imaging tumour cell heterogeneity following cell transplantation into optically clear immune-deficient zebrafish
Cancers contain a wide diversity of cell types that are defined by differentiation states, genetic mutations and altered epigenetic programmes that impart functional diversity to individual cells. Elevated tumour cell heterogeneity is linked with progression, therapy resistance and relapse. Yet, ima...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735845/ https://www.ncbi.nlm.nih.gov/pubmed/26790525 http://dx.doi.org/10.1038/ncomms10358 |