Detecting O(2) binding sites in protein cavities

Internal cavities are important elements in protein structure, dynamics, stability and function. Here we use NMR spectroscopy to investigate the binding of molecular oxygen (O(2)) to cavities in a well-studied model for ligand binding, the L99A mutant of T4 lysozyme. On increasing the O(2) concentra...

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Detalles Bibliográficos
Autores principales: Kitahara, Ryo, Yoshimura, Yuichi, Xue, Mengjun, Kameda, Tomoshi, Mulder, Frans A. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735865/
https://www.ncbi.nlm.nih.gov/pubmed/26830762
http://dx.doi.org/10.1038/srep20534

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735865/
https://www.ncbi.nlm.nih.gov/pubmed/26830762
http://dx.doi.org/10.1038/srep20534

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