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Detecting O(2) binding sites in protein cavities
Internal cavities are important elements in protein structure, dynamics, stability and function. Here we use NMR spectroscopy to investigate the binding of molecular oxygen (O(2)) to cavities in a well-studied model for ligand binding, the L99A mutant of T4 lysozyme. On increasing the O(2) concentra...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735865/ https://www.ncbi.nlm.nih.gov/pubmed/26830762 http://dx.doi.org/10.1038/srep20534 |