Nur77-mediated TRAF6 signalling protects against LPS-induced sepsis in mice

BACKGROUND: Nur77, a key member of the NR4A receptor subfamily, is involved in the regulation of inflammation and immunity. However, the in vivo regulatory roles of Nur77 in sepsis and the mechanisms involved remains largely elusive. In this study, we used Nur77-deficient (Nur77(−/−)) mice and inves...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Xiu-Ming, Zhang, Shen, He, Xiao-Shun, Guo, Peng-Da, Lu, Xing-Xing, Wang, Jing-Ru, Li, Jian-Ming, Wu, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735956/
https://www.ncbi.nlm.nih.gov/pubmed/26839514
http://dx.doi.org/10.1186/s12950-016-0112-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735956/
https://www.ncbi.nlm.nih.gov/pubmed/26839514
http://dx.doi.org/10.1186/s12950-016-0112-9

Ejemplares similares