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Computational Analysis of the Binding Specificities of PH Domains

Pleckstrin homology (PH) domains share low sequence identities but extremely conserved structures. They have been found in many proteins for cellular signal-dependent membrane targeting by binding inositol phosphates to perform different physiological functions. In order to understand the sequence-s...

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Detalles Bibliográficos
Autores principales: Jiang, Zhi, Liang, Zhongjie, Shen, Bairong, Hu, Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735990/
https://www.ncbi.nlm.nih.gov/pubmed/26881206
http://dx.doi.org/10.1155/2015/792904