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A Copy Number Variant on Chromosome 20q13.3 Implicated in Thinness and Severe Obesity

Background/Objectives. To identify copy number variants (CNVs) which are associated with body mass index (BMI). Subjects/Methods. CNVs were identified using array comparative genomic hybridization (aCGH) on members of pedigrees ascertained through severely obese (BMI ≥ 35 kg/m(2)) sib pairs (86 pedi...

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Detalles Bibliográficos
Autores principales: Hasstedt, Sandra J., Xin, Yuanpei, Mao, Rong, Lewis, Tracey, Adams, Ted D., Hunt, Steven C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736014/
https://www.ncbi.nlm.nih.gov/pubmed/26881067
http://dx.doi.org/10.1155/2015/623431