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Preventive Role of Endothelin Antagonist on Kidney Ischemia: Reperfusion Injury in Male and Female Rats

BACKGROUND: Renal ischemia/reperfusion injury (RIRI) is the most common cause of acute kidney injury. We tested the protective role of endothelin-1 receptor blocker; bosentan (BOS) in animal model of RIRI in two different genders. METHODS: Male and female Wistar rats were assigned as sham operated (...

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Detalles Bibliográficos
Autores principales: Afyouni, Nazgol Esmalian, Halili, Hanieh, Moslemi, Fatemeh, Nematbakhsh, Mehdi, Talebi, Ardeshir, Shirdavani, Soheila, Maleki, Maryam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736059/
https://www.ncbi.nlm.nih.gov/pubmed/26900442
http://dx.doi.org/10.4103/2008-7802.172549