Postprandial thermogenesis and respiratory quotient in response to galactose: comparison with glucose and fructose in healthy young adults

Circumstantial evidence suggests that substitution of glucose or sucrose by the low-glycaemic index sugar galactose in the diet may lead to greater thermogenesis and/or fat oxidation. Using ventilated hood indirect calorimetry, we investigated, in twelve overnight-fasted adults, the resting energy e...

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Autores principales: Charrière, Nathalie, Montani, Jean-Pierre, Dulloo, Abdul G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736092/
https://www.ncbi.nlm.nih.gov/pubmed/26855774
http://dx.doi.org/10.1017/jns.2015.41
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author Charrière, Nathalie
Montani, Jean-Pierre
Dulloo, Abdul G.
author_facet Charrière, Nathalie
Montani, Jean-Pierre
Dulloo, Abdul G.
author_sort Charrière, Nathalie
collection PubMed
description Circumstantial evidence suggests that substitution of glucose or sucrose by the low-glycaemic index sugar galactose in the diet may lead to greater thermogenesis and/or fat oxidation. Using ventilated hood indirect calorimetry, we investigated, in twelve overnight-fasted adults, the resting energy expenditure (REE) and respiratory quotient (RQ) for 30 min before and 150 min after ingestion of 500 ml of water containing 60 g of glucose, fructose or galactose in a randomised cross-over design. REE increased similarly with all three sugars, reaching peak values after 50–60 min, but its subsequent fall towards baseline values was faster with galactose and glucose than with fructose (P < 0·001). RQ increased with all three sugars, but to a much greater extent with galactose and fructose than with glucose, particularly after 1 h post-ingestion. When ingested as a sugary drink, postprandial thermogenesis and utilisation of fat after galactose are not higher than after glucose or fructose.
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spelling pubmed-47360922016-02-05 Postprandial thermogenesis and respiratory quotient in response to galactose: comparison with glucose and fructose in healthy young adults Charrière, Nathalie Montani, Jean-Pierre Dulloo, Abdul G. J Nutr Sci Brief Report Circumstantial evidence suggests that substitution of glucose or sucrose by the low-glycaemic index sugar galactose in the diet may lead to greater thermogenesis and/or fat oxidation. Using ventilated hood indirect calorimetry, we investigated, in twelve overnight-fasted adults, the resting energy expenditure (REE) and respiratory quotient (RQ) for 30 min before and 150 min after ingestion of 500 ml of water containing 60 g of glucose, fructose or galactose in a randomised cross-over design. REE increased similarly with all three sugars, reaching peak values after 50–60 min, but its subsequent fall towards baseline values was faster with galactose and glucose than with fructose (P < 0·001). RQ increased with all three sugars, but to a much greater extent with galactose and fructose than with glucose, particularly after 1 h post-ingestion. When ingested as a sugary drink, postprandial thermogenesis and utilisation of fat after galactose are not higher than after glucose or fructose. Cambridge University Press 2016-01-29 /pmc/articles/PMC4736092/ /pubmed/26855774 http://dx.doi.org/10.1017/jns.2015.41 Text en © The Author(s) 2016 http://creativecommons.org/licenses/by/4.0/ This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Brief Report
Charrière, Nathalie
Montani, Jean-Pierre
Dulloo, Abdul G.
Postprandial thermogenesis and respiratory quotient in response to galactose: comparison with glucose and fructose in healthy young adults
title Postprandial thermogenesis and respiratory quotient in response to galactose: comparison with glucose and fructose in healthy young adults
title_full Postprandial thermogenesis and respiratory quotient in response to galactose: comparison with glucose and fructose in healthy young adults
title_fullStr Postprandial thermogenesis and respiratory quotient in response to galactose: comparison with glucose and fructose in healthy young adults
title_full_unstemmed Postprandial thermogenesis and respiratory quotient in response to galactose: comparison with glucose and fructose in healthy young adults
title_short Postprandial thermogenesis and respiratory quotient in response to galactose: comparison with glucose and fructose in healthy young adults
title_sort postprandial thermogenesis and respiratory quotient in response to galactose: comparison with glucose and fructose in healthy young adults
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736092/
https://www.ncbi.nlm.nih.gov/pubmed/26855774
http://dx.doi.org/10.1017/jns.2015.41
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