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A new in vitro mouse oligodendrocyte precursor cell migration assay reveals a role for integrin-linked kinase in cell motility

BACKGROUND: The decline of remyelination in chronic multiple sclerosis (MS) is in part attributed to inadequate oligodendrocyte precursor cell (OPC) migration, a process governed by the extracellular matrix (ECM). Elucidating the mechanisms underlying OPC migration is therefore an important step tow...

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Detalles Bibliográficos
Autores principales: O’Meara, Ryan W., Cummings, Sarah E., Michalski, John-Paul, Kothary, Rashmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736119/
https://www.ncbi.nlm.nih.gov/pubmed/26831726
http://dx.doi.org/10.1186/s12868-016-0242-2