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Greater improvement in LRRK2 G2019S patients undergoing Subthalamic Nucleus Deep Brain Stimulation compared to non-mutation carriers

BACKGROUND: Bilateral subthalamic nucleus deep brain stimulation (STN-DBS) of parkinson’s disease (PD) patients has demonstrated to improve motor performance and to reduce dopa-induced dyskinesia. An association between the occurrence of dyskinesias and LRRK2 (leucine-rich repeat kinase 2) G2019S ge...

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Detalles Bibliográficos
Autores principales: Sayad, Massiva, Zouambia, Mohamed, Chaouch, Malika, Ferrat, Farida, Nebbal, Mustapha, Bendini, Mohamed, Lesage, Suzanne, Brice, Alexis, Brahim Errahmani, Mohamed, Asselah, Boualem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736184/
https://www.ncbi.nlm.nih.gov/pubmed/26831335
http://dx.doi.org/10.1186/s12868-016-0240-4