It Is All about (U)biquitin: Role of Altered Ubiquitin-Proteasome System and UCHL1 in Alzheimer Disease

Free radical-mediated damage to macromolecules and the resulting oxidative modification of different cellular components are a common feature of aging, and this process becomes much more pronounced in age-associated pathologies, including Alzheimer disease (AD). In particular, proteins are particula...

Descripción completa

Detalles Bibliográficos
Autores principales: Tramutola, Antonella, Di Domenico, Fabio, Barone, Eugenio, Perluigi, Marzia, Butterfield, D. Allan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736377/
https://www.ncbi.nlm.nih.gov/pubmed/26881020
http://dx.doi.org/10.1155/2016/2756068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736377/
https://www.ncbi.nlm.nih.gov/pubmed/26881020
http://dx.doi.org/10.1155/2016/2756068

Ejemplares similares