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It Is All about (U)biquitin: Role of Altered Ubiquitin-Proteasome System and UCHL1 in Alzheimer Disease
Free radical-mediated damage to macromolecules and the resulting oxidative modification of different cellular components are a common feature of aging, and this process becomes much more pronounced in age-associated pathologies, including Alzheimer disease (AD). In particular, proteins are particula...
Autores principales: | Tramutola, Antonella, Di Domenico, Fabio, Barone, Eugenio, Perluigi, Marzia, Butterfield, D. Allan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736377/ https://www.ncbi.nlm.nih.gov/pubmed/26881020 http://dx.doi.org/10.1155/2016/2756068 |
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