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Notch1 Pathway Protects against Burn-Induced Myocardial Injury by Repressing Reactive Oxygen Species Production through JAK2/STAT3 Signaling

Oxidative stress plays an important role in burn-induced myocardial injury, but the cellular mechanisms that control reactive oxygen species (ROS) production and scavenging are not fully understood. This study demonstrated that blockade of Notch signaling via knockout of the transcription factor RBP...

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Detalles Bibliográficos
Autores principales: Cai, Weixia, Yang, Xuekang, Han, Shichao, Guo, Haitao, Zheng, Zhao, Wang, Hongtao, Guan, Hao, Jia, Yanhui, Gao, Jianxin, Yang, Tao, Zhu, Xiongxiang, Hu, Dahai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736405/
https://www.ncbi.nlm.nih.gov/pubmed/27057278
http://dx.doi.org/10.1155/2016/5638943