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Luciferase mRNA Transfection of Antigen Presenting Cells Permits Sensitive Nonradioactive Measurement of Cellular and Humoral Cytotoxicity

Immunotherapy is rapidly evolving as an effective treatment option for many cancers. With the emerging fields of cancer vaccines and adoptive cell transfer therapies, there is an increasing demand for high-throughput in vitro cytotoxicity assays that efficiently analyze immune effector functions. Th...

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Detalles Bibliográficos
Autores principales: Omokoko, Tana A., Luxemburger, Uli, Bardissi, Shaheer, Simon, Petra, Utsch, Magdalena, Breitkreuz, Andrea, Türeci, Özlem, Sahin, Ugur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736447/
https://www.ncbi.nlm.nih.gov/pubmed/27057556
http://dx.doi.org/10.1155/2016/9540975