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Palladium‐Catalyzed Directed C(sp(3))–H Arylation of Saturated Heterocycles at C‐3 Using a Concise Optimization Approach

Saturated heterocycles, such as THFs, pyrrolidines, piperidines and THPs, are essential components of many biologically active compounds. Examples of C–H functionalization on these important ring systems remain scarce, especially at unactivated positions. Here we report the development of conditions...

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Detalles Bibliográficos
Autores principales: Affron, Dominic P., Bull, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY‐VCH Verlag 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736452/
https://www.ncbi.nlm.nih.gov/pubmed/26877706
http://dx.doi.org/10.1002/ejoc.201501300