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In Vitro Expansion of Bone Marrow Derived Mesenchymal Stem Cells Alters DNA Double Strand Break Repair of Etoposide Induced DNA Damage

Mesenchymal stem cells (MSCs) are of interest for use in diverse cellular therapies. Ex vivo expansion of MSCs intended for transplantation must result in generation of cells that maintain fidelity of critical functions. Previous investigations have identified genetic and phenotypic alterations of M...

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Detalles Bibliográficos
Autores principales: Hare, Ian, Gencheva, Marieta, Evans, Rebecca, Fortney, James, Piktel, Debbie, Vos, Jeffrey A., Howell, David, Gibson, Laura F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736568/
https://www.ncbi.nlm.nih.gov/pubmed/26880992
http://dx.doi.org/10.1155/2016/8270464