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The Rise of CRISPR/Cas for Genome Editing in Stem Cells

Genetic manipulation is a powerful tool to establish the causal relationship between a genetic lesion and a particular pathological phenotype. The rise of CRISPR/Cas9 genome-engineering tools overcame the traditional technical bottleneck for routine site-specific genetic manipulation in cells. To cr...

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Detalles Bibliográficos
Autores principales: Shui, Bing, Hernandez Matias, Liz, Guo, Yi, Peng, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736575/
https://www.ncbi.nlm.nih.gov/pubmed/26880991
http://dx.doi.org/10.1155/2016/8140168