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Glioblastoma Stem Cells Microenvironment: The Paracrine Roles of the Niche in Drug and Radioresistance

Among all solid tumors, the high-grade glioma appears to be the most vascularized one. In fact, “microvascular hyperplasia” is a hallmark of GBM. An altered vascular network determines irregular blood flow, so that tumor cells spread rapidly beyond the diffusion distance of oxygen in the tissue, wit...

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Detalles Bibliográficos
Autores principales: Fidoamore, Alessia, Cristiano, Loredana, Antonosante, Andrea, d'Angelo, Michele, Di Giacomo, Erica, Astarita, Carlo, Giordano, Antonio, Ippoliti, Rodolfo, Benedetti, Elisabetta, Cimini, Annamaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736577/
https://www.ncbi.nlm.nih.gov/pubmed/26880981
http://dx.doi.org/10.1155/2016/6809105