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Glioblastoma Stem Cells Microenvironment: The Paracrine Roles of the Niche in Drug and Radioresistance
Among all solid tumors, the high-grade glioma appears to be the most vascularized one. In fact, “microvascular hyperplasia” is a hallmark of GBM. An altered vascular network determines irregular blood flow, so that tumor cells spread rapidly beyond the diffusion distance of oxygen in the tissue, wit...
Autores principales: | Fidoamore, Alessia, Cristiano, Loredana, Antonosante, Andrea, d'Angelo, Michele, Di Giacomo, Erica, Astarita, Carlo, Giordano, Antonio, Ippoliti, Rodolfo, Benedetti, Elisabetta, Cimini, Annamaria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736577/ https://www.ncbi.nlm.nih.gov/pubmed/26880981 http://dx.doi.org/10.1155/2016/6809105 |
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