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Irbesartan Ameliorates Diabetic Nephropathy by Suppressing the RANKL-RANK-NF-κB Pathway in Type 2 Diabetic db/db Mice

The receptor activator of NF-κB ligand (RANKL) and its receptor RANK are overexpressed in focal segmental glomerular sclerosis (FSGS), IgA nephropathy (IgAN), and membranous nephropathy (MN). However, the expression and the potential roles of RANKL and RANK in diabetic nephropathy (DN) remain unclea...

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Detalles Bibliográficos
Autores principales: Chen, Xiao-Wen, Du, Xiao-Yan, Wang, Yu-Xian, Wang, Jian-Cheng, Liu, Wen-Ting, Chen, Wen-Jing, Li, Hong-Yu, Peng, Fen-Fen, Xu, Zhao-Zhong, Niu, Hong-Xin, Long, Hai-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736580/
https://www.ncbi.nlm.nih.gov/pubmed/26880862
http://dx.doi.org/10.1155/2016/1405924