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Revisiting Epithelial-to-Mesenchymal Transition in Liver Fibrosis: Clues for a Better Understanding of the “Reactive” Biliary Epithelial Phenotype

Whether liver epithelial cells contribute to the development of hepatic scarring by undergoing epithelial-to-mesenchymal transition (EMT) is a controversial issue. Herein, we revisit the concept of EMT in cholangiopathies, a group of severe hepatic disorders primarily targeting the bile duct epithel...

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Detalles Bibliográficos
Autores principales: Fabris, Luca, Brivio, Simone, Cadamuro, Massimiliano, Strazzabosco, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736590/
https://www.ncbi.nlm.nih.gov/pubmed/26880950
http://dx.doi.org/10.1155/2016/2953727