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Pharmacogenetics of Risperidone and Cardiovascular Risk in Children and Adolescents

Objective. To identify the frequency of obesity and metabolic complications in child and adolescent users of risperidone. Potential associations with clinical parameters and SNPs of the HTR2C, DRD2, LEP, LEPR, MC4R, and CYP2D6 genes were analyzed. Methods. Samples from 120 risperidone users (8–20 ye...

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Detalles Bibliográficos
Autores principales: Dos Santos-Júnior, Amilton, Henriques, Taciane Barbosa, de Mello, Maricilda Palandi, Della Torre, Osmar Henrique, Paes, Lúcia Arisaka, Ferreira-Neto, Adriana Perez, Sewaybricker, Letícia Esposito, Fontana, Thiago Salum, Celeri, Eloisa Helena Rubello Valler, Guerra-Júnior, Gil, Dalgalarrondo, Paulo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736591/
https://www.ncbi.nlm.nih.gov/pubmed/26880915
http://dx.doi.org/10.1155/2016/5872423