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Synergistic Effects of Cilostazol and Probucol on ER Stress-Induced Hepatic Steatosis via Heme Oxygenase-1-Dependent Activation of Mitochondrial Biogenesis

The selective type-3 phosphodiesterase inhibitor cilostazol and the antihyperlipidemic agent probucol have antioxidative, anti-inflammatory, and antiatherogenic properties. Moreover, cilostazol and probucol can regulate mitochondrial biogenesis. However, the combinatorial effect of cilostazol and pr...

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Detalles Bibliográficos
Autores principales: Chen, Yingqing, Pandiri, Indira, Joe, Yeonsoo, Kim, Hyo Jeong, Kim, Seul-Ki, Park, Jeongmin, Ryu, Jinhyun, Cho, Gyeong Jae, Park, Jeong Woo, Ryter, Stefan W., Chung, Hun Taeg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736599/
https://www.ncbi.nlm.nih.gov/pubmed/27057275
http://dx.doi.org/10.1155/2016/3949813