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Targeting autophagy to sensitive glioma to temozolomide treatment

Temozolomide (TMZ), an alkylating agent, is widely used for treating primary and recurrent high-grade gliomas. However, the efficacy of TMZ is often limited by the development of resistance. Recently, studies have found that TMZ treatment could induce autophagy, which contributes to therapy resistan...

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Detalles Bibliográficos
Autores principales: Yan, Yuanliang, Xu, Zhijie, Dai, Shuang, Qian, Long, Sun, Lunquan, Gong, Zhicheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736617/
https://www.ncbi.nlm.nih.gov/pubmed/26830677
http://dx.doi.org/10.1186/s13046-016-0303-5