Altered cellular localization and hemichannel activities of KID syndrome associated connexin26 I30N and D50Y mutations

BACKGROUND: Gap junctions facilitate exchange of small molecules between adjacent cells, serving a crucial function for the maintenance of cellular homeostasis. Mutations in connexins, the basic unit of gap junctions, are associated with several human hereditary disorders. For example, mutations in...

Descripción completa

Detalles Bibliográficos
Autores principales: Aypek, Hande, Bay, Veysel, Meşe, Gülistan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736630/
https://www.ncbi.nlm.nih.gov/pubmed/26831144
http://dx.doi.org/10.1186/s12860-016-0081-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736630/
https://www.ncbi.nlm.nih.gov/pubmed/26831144
http://dx.doi.org/10.1186/s12860-016-0081-0

Ejemplares similares