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Altered cellular localization and hemichannel activities of KID syndrome associated connexin26 I30N and D50Y mutations
BACKGROUND: Gap junctions facilitate exchange of small molecules between adjacent cells, serving a crucial function for the maintenance of cellular homeostasis. Mutations in connexins, the basic unit of gap junctions, are associated with several human hereditary disorders. For example, mutations in...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736630/ https://www.ncbi.nlm.nih.gov/pubmed/26831144 http://dx.doi.org/10.1186/s12860-016-0081-0 |