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Serum levels of 14-3-3η protein supplement C-reactive protein and rheumatoid arthritis-associated antibodies to predict clinical and radiographic outcomes in a prospective cohort of patients with recent-onset inflammatory polyarthritis

BACKGROUND: Age, C-Reactive Protein (CRP) and autoantibodies (Abs) are associated with worse prognosis in patients with recent-onset inflammatory polyarthritis (EPA). Serum 14-3-3η protein is a joint-derived biomarker that up-regulates cytokines and enzymes that perpetuate local and systemic inflamm...

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Detalles Bibliográficos
Autores principales: Carrier, Nathalie, Marotta, Anthony, de Brum-Fernandes, Artur J., Liang, Patrick, Masetto, Ariel, Ménard, Henri A., Maksymowych, Walter P., Boire, Gilles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736641/
https://www.ncbi.nlm.nih.gov/pubmed/26832367
http://dx.doi.org/10.1186/s13075-016-0935-z