Low oxygen tension reverses antineoplastic effect of iron chelator deferasirox in human glioblastoma cells

BACKGROUND: Overcoming resistance to treatment is an essential issue in many cancers including glioblastoma (GBM), the deadliest primary tumor of the central nervous system. As dependence on iron is a key feature of tumor cells, using chelators to reduce iron represents an opportunity to improve con...

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Detalles Bibliográficos
Autores principales: Legendre, Claire, Avril, Sylvie, Guillet, Catherine, Garcion, Emmanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736662/
https://www.ncbi.nlm.nih.gov/pubmed/26832741
http://dx.doi.org/10.1186/s12885-016-2074-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736662/
https://www.ncbi.nlm.nih.gov/pubmed/26832741
http://dx.doi.org/10.1186/s12885-016-2074-y

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