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Low oxygen tension reverses antineoplastic effect of iron chelator deferasirox in human glioblastoma cells
BACKGROUND: Overcoming resistance to treatment is an essential issue in many cancers including glioblastoma (GBM), the deadliest primary tumor of the central nervous system. As dependence on iron is a key feature of tumor cells, using chelators to reduce iron represents an opportunity to improve con...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736662/ https://www.ncbi.nlm.nih.gov/pubmed/26832741 http://dx.doi.org/10.1186/s12885-016-2074-y |