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Syndecan-1 (CD138) deficiency increases Staphylococcus aureus infection but has no effect on pathology in a mouse model of peritoneal dialysis

BACKGROUND: Technique failure in peritoneal dialysis (PD) due to fibrosis and angiogenesis is complicated by peritonitis. Staphylococcus aureus infection is one of the most common causes of peritonitis in PD. The heparan sulfate proteoglycan, syndecan-1 (CD138), was reported to regulate fibrosis, an...

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Detalles Bibliográficos
Autores principales: Kowalewska, Paulina M., Nguyen, Uyen T., Burrows, Lori L., Fox-Robichaud, Alison E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736699/
https://www.ncbi.nlm.nih.gov/pubmed/26832929
http://dx.doi.org/10.1186/s12929-016-0232-9