Cargando…

Killing Me Softly: Connotations to Unfolded Protein Response and Oxidative Stress in Alzheimer's Disease

This review is focused on the possible causes of mitochondrial dysfunction in AD, underlying molecular mechanisms of this malfunction, possible causes and known consequences of APP, Aβ, and hyperphosphorylated tau presence in mitochondria, and the contribution of altered lipid metabolism (nonsterol...

Descripción completa

Detalles Bibliográficos
Autores principales: Pająk, Beata, Kania, Elżbieta, Orzechowski, Arkadiusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736771/
https://www.ncbi.nlm.nih.gov/pubmed/26881014
http://dx.doi.org/10.1155/2016/1805304