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Killing Me Softly: Connotations to Unfolded Protein Response and Oxidative Stress in Alzheimer's Disease
This review is focused on the possible causes of mitochondrial dysfunction in AD, underlying molecular mechanisms of this malfunction, possible causes and known consequences of APP, Aβ, and hyperphosphorylated tau presence in mitochondria, and the contribution of altered lipid metabolism (nonsterol...
Autores principales: | Pająk, Beata, Kania, Elżbieta, Orzechowski, Arkadiusz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736771/ https://www.ncbi.nlm.nih.gov/pubmed/26881014 http://dx.doi.org/10.1155/2016/1805304 |
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