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FTIR study of CPD photolyase with substrate in single strand DNA

Photolyases (PHRs) utilize near UV/blue light to specifically repair the major photoproducts (PPs) of UV-induced damaged DNA. The cyclobutane pyrimidine dimer (CPD)-PHR binds flavin adenine dinucleotide (FAD) as a cofactor and repairs CPD lesions in double-stranded DNA. To understand the activation...

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Detalles Bibliográficos
Autores principales: Mahaputra Wijaya, I M., Iwata, Tatsuya, Yamamoto, Junpei, Hitomi, Kenichi, Iwai, Shigenori, Getzoff, Elizabeth D., Kandori, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society of Japan (BSJ) 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736783/
https://www.ncbi.nlm.nih.gov/pubmed/27493513
http://dx.doi.org/10.2142/biophysics.11.39