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Human Hepatocyte-Derived Induced Pluripotent Stem Cells: MYC Expression, Similarities to Human Germ Cell Tumors, and Safety Issues

Induced pluripotent stem cells (iPSC) are a most promising approach to the development of a hepatocyte transplantable mass sufficient to induce long-term correction of inherited liver metabolic diseases, thus avoiding liver transplantation. Their intrinsic self-renewal ability and potential to diffe...

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Detalles Bibliográficos
Autores principales: Unzu, Carmen, Friedli, Marc, Bosman, Alexis, Jaconi, Marisa E., Wildhaber, Barbara E., Rougemont, Anne-Laure
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736817/
https://www.ncbi.nlm.nih.gov/pubmed/26880963
http://dx.doi.org/10.1155/2016/4370142