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Analysis of Residual DSBs in Ataxia-Telangiectasia Lymphoblast Cells Initiating Apoptosis

In order to examine the relationship between accumulation of residual DNA double-strand breaks (DSBs) and cell death, we have used a control and an ATM (Ataxia-Telangiectasia Mutated) defective cell line, as Ataxia-Telangiectasia (AT) cells tend to accumulate residual DSBs at long times after damage...

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Detalles Bibliográficos
Autores principales: Anglada, Teresa, Terradas, Mariona, Hernández, Laia, Genescà, Anna, Martín, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736819/
https://www.ncbi.nlm.nih.gov/pubmed/27057549
http://dx.doi.org/10.1155/2016/8279560