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Liquid-theory analogy of direct-coupling analysis of multiple-sequence alignment and its implications for protein structure prediction
The direct-coupling analysis is a powerful method for protein contact prediction, and enables us to extract “direct” correlations between distant sites that are latent in “indirect” correlations observed in a protein multiple-sequence alignment. I show that the direct correlation can be obtained by...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Biophysical Society of Japan (BSJ)
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736835/ https://www.ncbi.nlm.nih.gov/pubmed/27493860 http://dx.doi.org/10.2142/biophysico.12.0_117 |