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Investigation of glycan evolution based on a comprehensive analysis of glycosyltransferases using phylogenetic profiling

Glycans play important roles in such cell-cell interactions as signaling and adhesion, including processes involved in pathogenic infections, cancers, and neurological diseases. Glycans are biosynthesized by multiple glycosyltransferases (GTs), which function sequentially. Excluding mucin-type O-gly...

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Detalles Bibliográficos
Autores principales: Tomono, Takayoshi, Kojima, Hisao, Fukuchi, Satoshi, Tohsato, Yukako, Ito, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society of Japan (BSJ) 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736839/
https://www.ncbi.nlm.nih.gov/pubmed/27493855
http://dx.doi.org/10.2142/biophysico.12.0_57