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Inhibition of Alveolar Macrophage Pyroptosis Reduces Lipopolysaccharide-induced Acute Lung Injury in Mice

BACKGROUND: Pyroptosis is the term for caspase-1-dependent cell death associated with pro-inflammatory cytokines. The role of alveolar macrophage (AM) pyroptosis in the pathogenesis of the acute lung injury and acute respiratory distress syndrome (ALI/ARDS) remains unclear. METHODS: C57BL/6 wild-typ...

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Detalles Bibliográficos
Autores principales: Wu, Dong-Dong, Pan, Pin-Hua, Liu, Ben, Su, Xiao-Li, Zhang, Le-Meng, Tan, Hong-Yi, Cao, Zu, Zhou, Zuo-Ren, Li, Hai-Tao, Li, Hao-Si, Huang, Li, Li, Yuan-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736856/
https://www.ncbi.nlm.nih.gov/pubmed/26415803
http://dx.doi.org/10.4103/0366-6999.166039