Effect of Ranirestat on Sensory and Motor Nerve Function in Japanese Patients with Diabetic Polyneuropathy: A Randomized Double-Blind Placebo-Controlled Study

We conducted a 26-week oral-administration study of ranirestat (an aldose reductase inhibitor) at a once-daily dose of 20 mg to evaluate its efficacy and safety in Japanese patients with diabetic polyneuropathy (DPN). The primary endpoint was summed change in sensory nerve conduction velocity (NCV)...

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Detalles Bibliográficos
Autores principales: Satoh, Jo, Kohara, Nobuo, Sekiguchi, Kenji, Yamaguchi, Yasuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Clinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736957/
https://www.ncbi.nlm.nih.gov/pubmed/26881251
http://dx.doi.org/10.1155/2016/5383797

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736957/
https://www.ncbi.nlm.nih.gov/pubmed/26881251
http://dx.doi.org/10.1155/2016/5383797

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