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Transplantation of Neural Stem Cells Cotreated with Thyroid Hormone and GDNF Gene Induces Neuroprotection in Rats of Chronic Experimental Allergic Encephalomyelitis

The present study investigates whether transplantation of NSCs treated with T3 alone (T3/NSCs), or in conjunction with GDNF gene (GDNF-T3/NSCs), provides a better therapeutic effect than NSCs for chronic EAE. EAE rats were, respectively, injected with NSCs, T3/NSCs, GDNF-T3/NSCs, and saline at 10 da...

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Detalles Bibliográficos
Autores principales: Gao, Xiaoqing, Hu, Guangqiang, Deng, Li, Fan, Guangbi, Yang, Chaoxian, Du, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736966/
https://www.ncbi.nlm.nih.gov/pubmed/26881104
http://dx.doi.org/10.1155/2016/3081939