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Time-Lapse Retinal Ganglion Cell Dendritic Field Degeneration Imaged in Organotypic Retinal Explant Culture

PURPOSE: To develop an ex vivo organotypic retinal explant culture system suitable for multiple time-point imaging of retinal ganglion cell (RGC) dendritic arbors over a period of 1 week, and capable of detecting dendrite neuroprotection conferred by experimental treatments. METHODS: Thy1-YFP mouse...

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Detalles Bibliográficos
Autores principales: Johnson, Thomas V., Oglesby, Ericka N., Steinhart, Matthew R., Cone-Kimball, Elizabeth, Jefferys, Joan, Quigley, Harry A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736988/
https://www.ncbi.nlm.nih.gov/pubmed/26811145
http://dx.doi.org/10.1167/iovs.15-17769