Cargando…

Time-Lapse Retinal Ganglion Cell Dendritic Field Degeneration Imaged in Organotypic Retinal Explant Culture

PURPOSE: To develop an ex vivo organotypic retinal explant culture system suitable for multiple time-point imaging of retinal ganglion cell (RGC) dendritic arbors over a period of 1 week, and capable of detecting dendrite neuroprotection conferred by experimental treatments. METHODS: Thy1-YFP mouse...

Descripción completa

Detalles Bibliográficos
Autores principales:	Johnson, Thomas V., Oglesby, Ericka N., Steinhart, Matthew R., Cone-Kimball, Elizabeth, Jefferys, Joan, Quigley, Harry A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2016
Materias:	Glaucoma
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736988/ https://www.ncbi.nlm.nih.gov/pubmed/26811145 http://dx.doi.org/10.1167/iovs.15-17769

Ejemplares similares

Regional Retinal Ganglion Cell Axon Loss in a Murine Glaucoma Model
por: Schaub, Julie A., et al.
Publicado: (2017)

Measuring Deformation in the Mouse Optic Nerve Head and Peripapillary Sclera
por: Nguyen, Cathy, et al.
Publicado: (2017)

Age-Related Changes in Quantitative Strain of Mouse Astrocytic Lamina Cribrosa and Peripapillary Sclera Using Confocal Microscopy in an Explant Model
por: Nguyen, Cathy, et al.
Publicado: (2018)

Long-Term Effects on Retinal Structure and Function in a Mouse Endothelin-1 Model of Retinal Ganglion Cell Degeneration
por: Lakshmanan, Yamunadevi, et al.
Publicado: (2023)

Losartan Treatment Protects Retinal Ganglion Cells and Alters Scleral Remodeling in Experimental Glaucoma
por: Quigley, Harry A., et al.
Publicado: (2015)

Diabetes Exacerbates the Intraocular Pressure-Independent Retinal Ganglion Cells Degeneration in the DBA/2J Model of Glaucoma
por: Amato, Rosario, et al.
Publicado: (2021)

Longitudinal In Vivo Changes in Retinal Ganglion Cell Dendritic Morphology After Acute and Chronic Optic Nerve Injury
por: Henderson, Delaney C. M., et al.
Publicado: (2021)

Physiologic Electrical Fields Direct Retinal Ganglion Cell Axon Growth In Vitro
por: Gokoffski, Kimberly K., et al.
Publicado: (2019)

Pressure-Induced Changes in Astrocyte GFAP, Actin, and Nuclear Morphology in Mouse Optic Nerve
por: Ling, Yik Tung Tracy, et al.
Publicado: (2020)

Retinal Astrocytes and GABAergic Wide-Field Amacrine Cells Express PDGFRα: Connection to Retinal Ganglion Cell Neuroprotection by PDGF-AA
por: Takahama, Shokichi, et al.
Publicado: (2017)

Scleral fibroblast response to experimental glaucoma in mice
por: Oglesby, Ericka N., et al.
Publicado: (2016)

Intraocular Pressure Elevation Compromises Retinal Ganglion Cell Light Adaptation
por: Tao, Xiaofeng, et al.
Publicado: (2020)

The Contribution of Sulfated Glycosaminoglycans to the Inflation Response of the Human Optic Nerve Head
por: Midgett, Dan E., et al.
Publicado: (2018)

Spatial Summation in the Glaucomatous Macula: A Link With Retinal Ganglion Cell Damage
por: Montesano, Giovanni, et al.
Publicado: (2023)

Induced Pluripotent Stem Cells Promote Retinal Ganglion Cell Survival After Transplant
por: Wu, Suqian, et al.
Publicado: (2018)

The Relationship Between Macula Retinal Ganglion Cell Density and Visual Function in the Nonhuman Primate
por: Antwi-Boasiako, Kwame, et al.
Publicado: (2021)

Microfluidic Platforms Promote Polarization of Human-Derived Retinal Ganglion Cells That Model Axonopathy
por: Boal, Andrew M., et al.
Publicado: (2023)

Neuroprotection of Retinal Ganglion Cells Suppresses Microglia Activation in a Mouse Model of Glaucoma
por: Kumar, Sandeep, et al.
Publicado: (2023)

Analyses of transplanted human retinal ganglion cell morphology and localization in murine organotypic retinal explant culture
por: Zhang, Kevin Y., et al.
Publicado: (2022)

Comparing Structure-Function Relationships Based on Drasdo's and Sjöstrand's Retinal Ganglion Cell Displacement Models
por: Hirasawa, Kazunori, et al.
Publicado: (2020)

Keratin8 Deficiency Aggravates Retinal Ganglion Cell Damage Under Acute Ocular Hypertension
por: Zhang, Chengshou, et al.
Publicado: (2023)

RGC-Net: An Automatic Reconstruction and Quantification Algorithm for Retinal Ganglion Cells Based on Deep Learning
por: Ma, Rui, et al.
Publicado: (2023)

Mice with an induced mutation in collagen 8A2 develop larger eyes and are resistant to retinal ganglion cell damage in an experimental glaucoma model
por: Steinhart, Matthew R., et al.
Publicado: (2012)

Pregabalin Mediates Retinal Ganglion Cell Survival From Retinal Ischemia/Reperfusion Injury Via the Akt/GSK3β/β-Catenin Signaling Pathway
por: Xu, Jing, et al.
Publicado: (2022)

TBK1 Knockdown Alleviates Axonal Transport Deficits in Retinal Ganglion Cells Via mTORC1 Activation in a Retinal Damage Mouse Model
por: Ye, Meng, et al.
Publicado: (2023)

The Effects of Glaucoma on the Pressure-Induced Strain Response of the Human Lamina Cribrosa
por: Midgett, Dan, et al.
Publicado: (2020)

T and B Lymphocyte Deficiency in Rag1−/− Mice Reduces Retinal Ganglion Cell Loss in Experimental Glaucoma
por: Gramlich, Oliver W., et al.
Publicado: (2020)

Morphometric Analysis of Retinal Ganglion Cell Axons in Normal and Glaucomatous Brown Norway Rats Optic Nerves
por: Goyal, Vidisha, et al.
Publicado: (2023)

Characterizing the Collagen Network Structure and Pressure-Induced Strains of the Human Lamina Cribrosa
por: Ling, Yik Tung Tracy, et al.
Publicado: (2019)

Microtubule Imaging Reveals Cytoskeletal Deficit Predisposing the Retinal Ganglion Cell Axons to Atrophy in DBA/2J
por: Sharoukhov, Denis, et al.
Publicado: (2018)

Relationship Between Macular Ganglion Cell Thickness and Ocular Elongation as Measured by Axial Length and Retinal Artery Position
por: Omoto, Takashi, et al.
Publicado: (2020)

Biological Correlations and Confounders for Quantification of Retinal Ganglion Cells by Optical Coherence Tomography Based on Studies of Outbred Mice
por: Hedberg-Buenz, Adam, et al.
Publicado: (2022)

Long-Term Protection of Retinal Ganglion Cells and Visual Function by Brain-Derived Neurotrophic Factor in Mice With Ocular Hypertension
por: Feng, Liang, et al.
Publicado: (2016)

Variation in Retinal Nerve Fiber Layer and Ganglion Cell Complex Associated With Optic Nerve Head Size in Healthy Eyes
por: Li, Caixia, et al.
Publicado: (2023)

Neuroretinal Rim Response to Transient Intraocular Pressure Challenge Predicts the Extent of Retinal Ganglion Cell Loss in Experimental Glaucoma
por: Patel, Nimesh B., et al.
Publicado: (2023)

Involvement of c-Jun N-terminal kinase 2 (JNK2) in Endothelin-1 (ET-1) Mediated Neurodegeneration of Retinal Ganglion Cells
por: Kodati, Bindu, et al.
Publicado: (2021)

Longitudinal Analysis of Retinal Ganglion Cell Damage at Individual Axon Bundle Level in Mice Using Visible-Light Optical Coherence Tomography Fibergraphy
por: Grannonico, Marta, et al.
Publicado: (2023)

Asymmetry of Peripapillary Retinal Blood Vessel and Retinal Nerve Fiber Layer Thickness Between Healthy Right and Left Eyes
por: Quach, Jack, et al.
Publicado: (2023)

The Relationship Between Optic Disc and Retinal Artery Position and Glaucomatous Visual Field Progression
por: Fujino, Yuri, et al.
Publicado: (2021)

Normative Percentiles of Retinal Nerve Fiber Layer Thickness and Glaucomatous Visual Field Loss
por: Singh, Rishabh, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_ifo9k8aj1b8gcabi4j97plci6p