ES‐62 Protects Against Collagen‐Induced Arthritis by Resetting Interleukin‐22 Toward Resolution of Inflammation in the Joints

OBJECTIVE: The parasitic worm–derived immunomodulator ES‐62 protects against disease in the mouse collagen‐induced arthritis (CIA) model of rheumatoid arthritis (RA) by suppressing pathogenic interleukin‐17 (IL‐17) responses. The Th17‐associated cytokine IL‐22 also appears to have a pathogenic role...

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Detalles Bibliográficos
Autores principales: Pineda, Miguel A., Rodgers, David T., Al‐Riyami, Lamyaa, Harnett, William, Harnett, Margaret M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2014
Materias:
Experimental Arthritis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737104/
https://www.ncbi.nlm.nih.gov/pubmed/24497523
http://dx.doi.org/10.1002/art.38392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737104/
https://www.ncbi.nlm.nih.gov/pubmed/24497523
http://dx.doi.org/10.1002/art.38392

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