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Investigating the function of F(c)‐specific binding of IgM to P lasmodium falciparum erythrocyte membrane protein 1 mediating erythrocyte rosetting

Acquired protection from P lasmodium falciparum malaria takes years to develop, probably reflecting the ability of the parasites to evade immunity. A recent example of this is the binding of the F(c) region of IgM to VAR2CSA‐type PfEMP1. This interferes with specific IgG recognition and phagocytosis...

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Detalles Bibliográficos
Autores principales: Stevenson, Liz, Huda, Pie, Jeppesen, Anine, Laursen, Erik, Rowe, J. Alexandra, Craig, Alister, Streicher, Werner, Barfod, Lea, Hviid, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737123/
https://www.ncbi.nlm.nih.gov/pubmed/25482886
http://dx.doi.org/10.1111/cmi.12403